NORFLOX EYE DROP 0.3 % (5 ML) EYE DROP : Norflox eye drop is sterile preparations of norfloxacin(a broad-spectrum fluoroquinolone antibacterial) used for the treatment of conjunctivitis and in case of an ear, it is recommended for acute otitis media, chronic suppurative otitis media, Otitis externa, and prophylaxis during otic surgeries(mastoid surgery.
Composition: Each ml of Norflox eye drop 0.3 % (5 ML) contains 0.3 % w / v Norfloxacin USP, 0.01 % w / v Benzalkonium chloride NF(preservative), and Sterile aqueous vehicle
How does it work: Norfloxacin has in vitro activity against a broad spectrum of gram-positive and gram-negative aerobic bacteria.its bactericidal effect inhibits ATP dependent DNA supercoiling reaction catalyzed by the DNA gyrase(an enzyme involved in DNA replication), inhibits the relaxation of supercoiled DNA, and promote double-stranded DNA breakage. Fluorine atom helps increased potency against gram - negative organisms, and the piperazine moiety works for anti pseudomonal activity.
How to use this: In the case of an adult and pediatric patients, Norflox eye drop is usually recommended to be used topically to the affected eye or eyes in one or two drops four times daily for a week. On the basis of the severity of the infections, the dosage for the first day of therapy might be one or two drops every two hours.
Side Effects: While clinical trials, the most common drug - related adverse reaction can be discomfort or local burning.Other side effects can be conjunctival hyperemia, bitter taste, chemosis, and photophobia etc.
Precautions and Warnings: If you are a hypersensitivity to norfloxacin or other members of quinolone group of antibacterial agents or if you are a pregnant woman, consult your health specialist before using Norflox eye drop - 0.3 % (5 ML). Hypersensitive patients reported a loss of consciousness, tingling, urticarial, loss of consciousness, pharyngeal, itching etc.following the first dose of the drug. In case of a pregnant woman, this medicine can be used only if the potential benefit justifies the potential risk to the fetus. The impact of norfloxacin while lactation is unknown so one should either discontinue nursing or discontinue this drug(depends on the severity of your condition).